EXO-NET is the exosome capture technology of choice.
Sample preparation methods for clinical diagnostics based on liquid biopsies need to be robust, operator independent, reliable and rapid, and highly scalable. These characteristics are also critical for research applications. A review of the current technologies available for capture of exosomes (Table 1) shows that only EXO-NET™ technology meets all of these requirements.
Table 1. Comparison of currently available exosome isolation techniques with EXO-NET.
*SEC= size exclusion chromatography
WHAT ARE THE BENEFITS OF EXO-NET FOR YOUR RESEARCH?
You should choose EXO-NET for your exosome capture:
If you need highly concentrated and highly pure exosomes in less than 15 minutes.
If you want to improve the efficiency and/or scalability of your exosome capture
If you need an exosome purification method that is capable of being used in downstream diagnostic assays.
If you are looking for lipid, RNA or protein biomarkers from exosomes.
If your research involves serum, plasma, urine, saliva or tissue culture supernatant and want a universal exosome isolation method.
If you need to translate your exosome sample prep from ultracentrifugation or other cumbersome or time-consuming exosome preparation methods.
If you want very low bias in your preparation method.
The EXO-NET™ technology demonstrates superior exosome capture ability in comparison to a commercial competitor, as evidenced by the concentration of known CD63 and CD9 exosome specific biomarkers.
In addition to demonstrating outperformance compared to commercial products, EXO-NET™ demonstrated outperformance against ultra-centrifugation (the recognized research gold-standard method), in a fraction of the time (15 minutes versus 6-12 hours).
- Emily Stein and Peter French (2020),
'Enhanced biomarker capture performance by a novel molecular matrix (“Molecular Net”) for liquid biopsy applications can be explained by the Turing effect'